wild dagga resins and tinctures

Buy Wild Dagga resins HERE

Leonurine, an improved synthesis –

Cheng KF, Yip CS, Yeung HW, Kong YC.

Leonurine (1) is the uterotonic principle of Leonurus artemisia. We have developed a simple, high-yield synthetic procedure of 1 that is adaptable to large scale preparation. The synthesis involves the condensation of syringic acid and 4-guanidino-1-butanol hydrochloride in the presence of DDC using 1:1 HMPT-ether as solvent. The synthetic leonurine showed uterotonic activity in vivo and in vitro.

The uterotonic principle of Leonurus artemisia, a plant leaf, is leonurine. This paper reports the development of a simple, high-yield synthetic procedure of reproducing leonurine that is adaptable to large-scale preparation. The synthetic process includes condensation of syringic acid and 4-guanidino-1-butanol hydrochloride in the presence of dicyclohexylcarbodiimide, using 1:1 hexamethylphosphoric triamide-ethyl ether as solvent. Synthetic leonourine showed uterotonic activity in vitro and in vivo, just like its naturally occurring counterpart.

Leonurine is easily extracted into water and its derivative compound is hydrochloride monohydrate.  Primary uses include (1) Respiratory tract infections caused by Streptococcus pneumoniae and group A ß-hemolytic streptococci. (2) Otitis media due to S. pneumoniae, Hemophilus influenzae, Moraxella catarrhalis (use monohydrate only), staphylococci, streptococci, and N. catarrhalis. (3) GU infections (including acute prostatitis) due to Escherichia coli, Proteus mirabilis or Klebsiella species. (4) Bone infections caused by P. mirabilis or staphylococci. (5) Skin and skin structure infections due to staphylococci and streptococci.


Further Articles for Wild Dagga
wild dagga of south africa
Dispelling Wild Dagga Species Confusion
The Diterpenoids of Leonurus leonotus
Dagga/Yopo Experience Report
Folk, Traditional, and Medical Uses for Wild Dagga
Growing Wild Dagga
Botany of Leonurus (Mint Family)
Hottentot Tribe and Wild Dagga
Motherwort – The True Dagga Plant
Hottentot Tribe and Wild Dagga